Do I Need an Aromatase Inhibitor AI?
Aromatase inhibitor therapy has side effects that may affect your quality of life. If you’re taking an aromatase inhibitor, ask your healthcare provider about ways to reduce side effects so you can continue treatment that helps you live free of breast cancer. As the population of breast cancer survivors continues to grow, attention to supporting patients is paramount to providers’ practice.
- Just as you’re beginning a new chapter in your life, you’re told you have cancer.
- Surgical removal of the ovaries is a permanent way to reduce the levels of oestrogen.
- In this post, we do a deep dive into what aromatase inhibitors are, what they are used for, and which one is the best option for bodybuilding.
- While on the medication, there should be proper measures in place to prevent pregnancies.
- Studies demonstrating the effectiveness of broccoli in oestradiol inhibition required a hefty dose of 500g of broccoli.
Are there side effects from using aromatase inhibitors?
It is important to remember that the best TRT clinic knows the importance of estrogen to male physiology. The Alpha Hormones TRT clinic does not aim to inhibit estrogen production – only to maintain the right balance between testosterone and estrogen. If you still have questions about the cost of exemestane, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug.
Weight Loss Insights: Comparing Tirzepatide and Semaglutide for Effective Results
The following review of research has demonstrated significantly prolonged disease-free survival, time to recurrence, and reduced distant metastases and contralateral breast cancers by 40% with the use of AIs. Aromatase inhibitors are considered endocrine therapy because of their actions on the production of hormones in the body and their effect on the proliferation of breast cancer cells. The human aromatase enzyme is a member of the cytochrome P450 family and is the product of the CYP19A1 gene, located on chromosome 15 17, 18. It functions to catalyze the rate-limiting and final step of estrogen biosynthesis; the aromatization of androgens to estrogens.
But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. And don’t stop using Arimidex unless your doctor recommends it. By the outpouring of interest, I knew it had struck a nerve with those fighting breast cancer and that’s exactly what I intended to do. If you do show signs of bone thinning (osteopenia) or weakening (osteoporosis) you may need to see your GP or specialist for special treatment https://www.lucyhotel.gr/steroids-understanding-their-use-and-implications-20/ for your bones. Tamoxifen can increase fertility so you must use contraception while you are taking tamoxifen if you have not been through menopause. Use a barrier method such as condoms, a diaphragm or a non-hormonal intra-uterine device (IUD).
Aromasin for bodybuilding (not a legal use)
Estrogen blockers can help to keep more testosterone in the body circulating so that the body can work more efficiently. Dr. Mohammed Fouda is a renowned neurosurgeon with a wealth of experience and expertise. He graduated from Ain Shams University and completed postdoctoral fellowships at Harvard and Johns Hopkins. He has published over 15 peer-reviewed articles and is a medical reviewer for 9 prestigious neurosurgical journals. He serves as an official medical reviewer for our website content. His expertise ensures the accuracy and credibility of the information presented.
This is more pronounced in obese males who have a significant amount of fat cells that have a lot of aromatase. Even though aromatase inhibitors have been used for many years, more time is still needed to assess the long-term risks of these drugs. Although both aromatase inhibitors and tamoxifen can cause menopausal symptoms such as hot flashes, many of their side effects differ (see the table below). Your health care provider may also switch you to another aromatase inhibitor (you may have less pain with a different drug) or recommend tamoxifen 6. If you have joint or muscle pain while taking an aromatase inhibitor, talk with your health care provider.